The power and pitfalls of omics part 2: epigenomics, transcriptomics and ME/CFS
Simon McGrath concludes his blog about the remarkable Prof George Davey Smith's smart ideas for understanding diseases, which may soon be applied to ME/CFS.
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xmrv or dysfunctional immune system

Discussion in 'Antivirals, Antibiotics and Immune Modulators' started by heapsreal, Jul 3, 2010.

  1. muffin

    muffin Senior Member

    Intunejune: "Primary immune deficiencies are also "in the genes."

    I too agree that a large subset of CFIDS people have genetic issues esp. with their immune system (Mitochondria damage/dysregulation). All i have to do is to look back to my father, his mother, his brother, and the odd tales of previous generations and I can not help but believe there is a rather large component to CFIDS. Now, not all people who get CFIDS will have that genetic damage right out out of the womb - like my husband who must have gotten the virus/pathogen from living with me for 10 years and then got sick for the next 6 years - I have been sick 16 years. I would bet that another subgroup acquires this virus (or other viruses) from contact since apparently XMRV is highly contagious but has a long incubation period. That would make sense with my husband and living with me for ten years, immense stress that damaged his immune system, a virus of some sort, and bang, down he went and has not gotten back up in six years.

    Dr. Jonathan Kerr identified those genes that were up and down -regulated.
  2. IntuneJune

    IntuneJune Senior Member

    NorthEastern USA

    Or is it spelled, intertwined...... the more I read up on the "facts, the more confused I get, and when I am reading about .... let's say FMS, I run into information that could be for PIDD, or help for celiacs, or was that hypothyroidism, circles, coming and going, I think I just saw the backside of me going out that other door, but I am just walking into the room.

    Am I turned around, or is the information turned around, or is it the same......

    Yes Muffin, it is curious. I just returned from my date with the IV pole.


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