I know xmrv is a hot topic, but depending on which study(positive) its only 67% positive for xmrv, theres still 33% with cfs and no xmrv. I still cant help but think we have a dysfunctional immune system which leaves us open to different infections, maybe any infection found in cfs people are just opportunistic because of our poorly functioning immune system. Dr lerners latest study shows some appear to just have chronic ebv, ebv is usually controlled by an intact immune system. I have read in the past where some guru cfs docs as a last resort have used gamma globulins and immunoglobulins with success,, these have a general affect in strengthening the immune system, and to a lesser extent immunovir has had a modest amount of success. Has anyone had experience with immunoglobulins/gammaglobulins or got any links to recent studies involving these medicines. I believe we have cfids, chronic fatigue immune dysfunction syndrom it best describes us. It appears to me in my personal research that the most common abnormality found in cfids is nk cell dysfunction as well as other lymphocyte abnormalities either high or low. Of coarse a retrovirus could be causing this but with 33% not testing positive to xmrv, im starting to think its opportunistic. cheers!!!!!