Would you have a course of Rituximab infusions if you were offered them today? I just noticed a unfortunate aspect of the use of Ritux in ME - it seems it is not as effective in severe cases, yet these are the patients who would theoretically have the most to gain and the least to lose from it. My ME is only moderate, so at the moment I would want to explore other diagnoses/treatment options before I tried Rituximab. If these failed however, and my condition did not improve or even worsened, I would definitely consider Rituximab, if it was available. Of course, people's decisions will be informed by research that is yet to be published, but I am just curious to see how many people would try it today given the chance.