"Systemic Exertion Intolerance Disease" or S.E.I.D. Sounds a lot better than CFS and perhaps better than ME/CFS if you insist on including the CFS bit. But can a committee (granted, one with several clinicians familiar with ME patients) simply describe a clinical entity? Wasn't that a significant part of the issue with CFS (and part of the resistance to ME)? We now have yet another set of diagnostic criteria. And yes, this criteria places PEM front and center. I do hope that there are plans to validate this new diagnostic criteria, if for no other reasons than to broaden acceptance but most importantly, to ensure that it is actually identifying the "right" group of patients (talk about a loaded term) and excluding the "wrong" patients (e.g. patients with a primary depression issue that have physical symptoms resulting from their depression). S.E.I.D. Self-reported - 1) Six months of profound, unexplained fatigue and 2) post-exertional malaise and 3) unrefreshing sleep and 4a) cognitive problems or 4b) “orthostatic intolerance” Would your doc be willing/able to diagnose S.E.I.D.?