After watching this you will see there are many causes of fatigue that can occurr in us, although i think with cfs/me we are more immune/infection related, i think this puts other things out of whack which are mentioned in the video. I think if one has a partial response to a certain treatment i think they need to hold onto that but also keep persuing other issues. I think with us when one thing go's wrong it can put us in a viscious cycle. This is why i think cfs/me is so hard to treat and why the average doctor has problems with treatments, because prozac isnt a one hit wonder. My experience is that going after infections has helped alot but sorting adrenal hormones, antioxidants, sleep etc etc all have apart in improving my function. Im now looking into thyroid as i have a constant low body temp under 36c, maybe a T3/reverse T3 problem but also optimising dhea/pregnenolone/cortisol can also improve thyroid function?? cheers!!!