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Why taking glutamine can make your sleep worse

Discussion in 'Sleep' started by Beyond, Oct 26, 2013.

  1. Beyond

    Beyond 10% of discount in iHerb!--> PEZ915

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    Murcia, Spain
    So following the many websites, studies and people saying that glutamine is the Holy Grail for leaky gut or IBD I jumped and bought a kilogram of glutamine. I was planning to take it for two months. Now I think it sucks. Why? Since taking it my insomnia is back. And I found this:

    http://www.sciencedirect.com/science/article/pii/S0899900702007748

    http://www.cortjohnson.org/blog/201...fs-puzzle-the-neuroinflammatory-series-pt-ii/

    I should have thought twice. I knew glutamate could be elevated by glutamine supplementation but didnĀ“t thought much of it. Now I realise this was causing my insomnia. I will give some of it to my brother and see what happens, if it affects him negatively too I will be dumping 40 dollars worth of glutamine. It is better than taking every morning a tablespoon of glutamate.

    @Valentijn the second link says N-acetylcsysteine (NAC) acts as a glutamate antagonist through facilitating the production of GABA. That might be why it helps you sleep!

    So, I feel stupid. :cautious: And actually angry at myself for being so impulsive. I feel like I have been eating these days large doses of MSG snacks, which I always avoid like the plague. But I hope someone learns something from my experience.
    Last edited: Oct 28, 2013
    Little Bluestem and Valentijn like this.
  2. Dreambirdie

    Dreambirdie work in progress

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    N. California
    Interesting. Thanks @Beyond for posting this.

    I have been taking glutamine every night for more than a year, for leaky gut. I struggle with insomnia all the time ,and now I wonder if that could be contributing to my agitated nerves..?

    Recently I began taking NAC each night and that seems to be helping me sleep a little better. Maybe it's time to chuck that glutamine completely.
    Beyond and Valentijn like this.
  3. Beyond

    Beyond 10% of discount in iHerb!--> PEZ915

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    Murcia, Spain
    I took it first thing in the morning, around 15 grams. Have seen in forums commented that it causes insomnia in other people too. I might consider taking less in the future and see but for now a good week without glutamine is needed to dillucidate if that was causing the worse sleep. Sleep is number one in my book after pain, but I am "lucky" because my pain is not-so-frequent.

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