International ME/CFS and FM Awareness Day Is On May 12, 2018
Thomas Hennessy, Jr., selected May 12th to be our international awareness day back in 1992. He knew that May 12th had also been the birthday of Florence Nightingale. She was the English army nurse who helped to found the Red Cross as well as the first school of nursing in the world.
Discuss the article on the Forums.

Why not compare Dectin-1 poloymorphisms in CFS/ME v. healthy controls

Discussion in 'The Gut: De Meirleir & Maes; H2S; Leaky Gut' started by GCODT, Jan 26, 2013.

  1. GCODT

    GCODT

    Messages:
    1
    Likes:
    0
    Hypothesis is that Dectin-1 gene mutation will be more prevalent in CFS than healthy controls.

    Proving this will strongly suggest that a subset of CFS (particularly with comorbid IBS) is caused by a chronic fungal infection in the context of genetic primary immune deficiency (the immune system is unable to fight off the fungus).

    http://www.cedars-sinai.edu/About-U...re-role-of-fungus-in-digestive-disorders.aspx

    LOS ANGELES (June 6, 2012) – Cedars-Sinai researchers say their examination of the fungi in the intestines suggests an important link between these microbes and inflammatory diseases such as ulcerative colitis.

    http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3432565/

    Mice lacking Dectin-1 exhibited increased susceptibility to chemically induced colitis, which was the result of altered responses to indigenous fungi. In humans, we identified a polymorphism in the gene for Dectin-1 (CLEC7A) that is strongly linked to a severe form of ulcerative colitis.
     

See more popular forum discussions.

Share This Page