The deep sleep deprivation is a definite part of this disease. I have had 4 slstudiesudys since 2004 and the highest amount of deep slow wave sleep is 9 mins. During that particular sleep study my sleep doctor had me on Ambien CR 12.5mg and 4.5 ml of Xyrem and slept almost 7 hours and got only 9 mins. of deep sleep. I got 0 mins on two of the other test and 5 mins on the other. Something with this disease malfunctions our sleep. Xyrem is not a guarantee of deep sleep with this disease. I have had 8 years of known deep sleep deprivation at this point and if there was a way to rate it. It would probably be a 6 out of 10 in 2004 and now I'm at a 2 out of 10 and cannot even no longer take Xyrem without getting very severe anxiety during the day.takesakes at least a week of being of the Xyrem for the anxiety to subside. My last sleep study also included the MSLT (Nap Test) the following day and it was moderate to severe narcolepsy with central apneas and some alpha intrusions. He said it was one of the most non-typical sleep patterns that he had ever seen. I do not think our sleep can be fixed till they determine what this disease is doing to us and start finding was to reverse or heal our bodies from it. I think it is he same reason we will not fix ouaxisA axix until we find some way to heal from this disease. We just have to do the best we can and hope, but I have just about ran out of hope. There will not be anything within the next 8 to 10 year and there is no way I'll be around here then. I'm donating my brain, spine or whatever they want and hopefully it will be beneficial to the rest of you.