The 12th Invest in ME Research Conference June, 2017, Part 2
MEMum presents the second article in a series of three about the recent 12th Invest In ME International Conference (IIMEC12) in London.
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Whole genome sequencing for $330 including interpretation

Discussion in 'Genetic Testing and SNPs' started by Waverunner, Feb 6, 2016.

  1. Waverunner

    Waverunner Senior Member

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  2. Old Bones

    Old Bones Senior Member

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    Hi @Waverunner I have only recently started to consider genetic testing, so know very little about the options. Could you please explain what you mean by "coverage is very low". Thanks.
     
  3. Valentijn

    Valentijn Senior Member

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    4x is very low coverage, so there would probably be a lot more errors. Something like 30x would be more standard, and 100x or greater would be extremely good.
     
  4. Sea

    Sea Senior Member

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    NSW Australia
    Good find thanks Waverunner.

    https://www.fullgenomes.com

    US dollars:
    10x = $725
    20x = $1200
    30x = $1650
    Interpretation = $50

    Hmmm... how to choose. How much coverage is accurate enough? The site says that the 1000 genomes project was done at 4-5x coverage.
     
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  5. Valentijn

    Valentijn Senior Member

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    I wouldn't go under 20x. And would be reluctant to go under 30x.

    When looking at thousands of genomes, throwing out a lot of "no-call" type results isn't a big deal. There are still plenty of good results for each SNP from other genomes. But for getting full data for a single genome, 4-5x isn't going to do it. And then it's a matter of whether or not the stuff it's missing or getting wrong are resulting in something important being missed.
     
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  6. Waverunner

    Waverunner Senior Member

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    Thanks for the info. Prices are still pretty good. Gene by gene wants $10,395.00 for WGS (coverage 30x) :rolleyes:.
    I wish there would be more competition in the market.
     
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