Hip
Senior Member
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Respectfully, I don't believe I could show you enough proof, because you don't believe LPS translocation is true.
I did not say I don't think LPS can translocate from the intestines into the bloodstream; that remains an open question; it's just that when I looked for evidence that it can translocate, I could not find any.
I am very interested in any evidence that you can shown me, because as mentioned, I have also speculated LPS leaking from the gut into the blood might be playing a role in ME/CFS.
If I can make better sense of a different theory, I will hop on that bus in a hurry!
Have you looked at the sickness behavior response, where infection/inflammation in the gut (or in other organs) is sensed vagus nerve, and signaled to the brain, where it causes the brain to ramp up the level of brain inflammation, as well as precipitating sickness behavior symptoms (the symptoms you feel when you come down with an infection like the flu).