Freddd I stand corrected, with a fair amount of searching, I did find information on titration going back to 2009, which is five years. I won't be saying that any more. However, I think my other points are still valid. People wouldn't be having misconceptions if the information wasn't so hard to find. What I (and I'm sure many others) would like to see is a web page or website (not a forum post) that I can link to which has the definitive, latest and greatest version of your protocol. Ideally, it would be something that you could edit as you refine the protocol. If that were done, I would be happy to include it in the collection of methylation links in my signature. Notice that I don't have your protocol listed - I have no idea what to link to.