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Which detox pathway handles enviromental allergies?
- Thread starter Bluelude1
- Start date
ljimbo423
Senior Member
- Messages
- 4,705
- Location
- United States, New Hampshire
I don't know the specific detox pathways for environmental allergies but here is a couple of diagrams of what's needed for phase 1 and phase 2 detox in the liver.
LINK
Jim
LINK
Jim
caledonia
Senior Member
- Messages
- 4,610
There are many pathways.
But generally speaking, what's happening is that Phase I detoxification is sped up, while Phase II is slowed down. This creates a bottleneck of toxins that can't be eliminated, which then causes various symptoms.
See also the document in my signature link called the "SNPs Interpretation Guide". Ignore the first part about methylation and skip to the Detox SNPs section.
It covers the various genes of Phase I and Phase II detox, and what substances each gene detoxifies.
Note that your while your genetics have some impact, you also have to take into account epigenetics, which is the environmental influence on your gene expression.
But generally speaking, what's happening is that Phase I detoxification is sped up, while Phase II is slowed down. This creates a bottleneck of toxins that can't be eliminated, which then causes various symptoms.
See also the document in my signature link called the "SNPs Interpretation Guide". Ignore the first part about methylation and skip to the Detox SNPs section.
It covers the various genes of Phase I and Phase II detox, and what substances each gene detoxifies.
Note that your while your genetics have some impact, you also have to take into account epigenetics, which is the environmental influence on your gene expression.