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Where can I buy LDN without a filler?

Discussion in 'General Treatment' started by mirijam, Nov 16, 2015.

  1. mirijam

    mirijam

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    I read that there are some companys, who sells LDN in a liquid form or as powder without a filler. But can´t find one, who sells to europe.
     
  2. Hip

    Hip Senior Member

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    Do you have any specific allergies or sensitivities tablet binders or fillers? If not, then note that some supplement companies are trying to cultivate irrational concerns and worries in the minds of consumers about binders or fillers, so that they can then sell them their own brand of filler-free supplements.
     
  3. minkeygirl

    minkeygirl But I Look So Good.

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    Here you would need a compounding pharmacy but they still have some filler. But it's one that doesn't cause sensitivities.
     
  4. ahmo

    ahmo Senior Member

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    I get naltrexone tablets from alldaychemist.com. I dilute them to make ldn. The filler stays at the bottom of the bottle. I decant into another container, pouring it through a piece of cloth, which catches the filler particles.
     
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  5. CantThink

    CantThink Senior Member

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    Here:
    https://www.buyldn.com/ldn-drops.html
     
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  6. mirijam

    mirijam

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    @Hip I'm starting to believe it..because I respond to so many drugs in the same way. I don´t know if it´s coincidental or there is something in it, I can´t tolerate.
    @ahmo hehe we wrote already, maybe it´s just normal, we will see.
    @CantThink this is interessting!! Do you think it´s possible to dilute the solution? Don´t want to increase it in 0.5mg steps
     
  7. mirijam

    mirijam

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    For sure this solution can be diluted, why not..I should know these things as a chemist..but most of the time I feel like this
     
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  8. ahmo

    ahmo Senior Member

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    :confused:

    If you get the 50ml tablets, you can dilute 50mg : 50ml distilled water. Then you've got 1mg/1ml, easy to use as little as you want, by the drop.
     
  9. mirijam

    mirijam

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    @ahmo this is what I've done
     
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  10. CantThink

    CantThink Senior Member

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    I reckon you can dilute it with distilled water and draw up with a syringe. I haven't tried this one yet as I'm in my 'off LDN period'. I shall probably buy from them at some point to try it. I used to buy liquid (Spanish), then that source dried up so I switched to tablets, and recently that source dried up. I quite liked the Spanish liquid version so would be happy to try another type.
     
  11. panckage

    panckage Senior Member

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    Is this because you find LDN loses its effects over time? If so what does your dosing schedule look like? How long do you wait before it starts working again?
     
  12. CantThink

    CantThink Senior Member

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    Yes.

    Originally I took a very long time to go from a starting dose of either 0.5 or 0.75, increasing in 0.25 increments, with the aim of reaching 4.5mg. When I started and every time I increased I got a herx reaction lasting between 5-7 days, during this time I was effectively bed bound - I could move around but I was so ill it was better to just lie there.

    So after the 5-7 day period, the herx would stop and I'd be back to normal. Over time I had improvements with LDN to the point where I was able to do a course and a class, and although I was still very ill from doing that I could actually physically get there, which would have been impossible before LDN. I was doing well enough that I was also planning on starting my own business (I still have the all the website sitting on my computer), then the LDN stopped working.

    I came off it for a while. I have fiddled around quite a bit since then trying various methods of taking it, and talked to others who had the same kind of experience.

    For me, it seems to work best when I feel very ill... Then I take it until I feel a lot better and stop seeing any improvements, and then I stop it until I feel ill enough to need it again.

    For example, earlier this year I was pretty much housebound and partially bedbound (was spending about 20 hours a day in bed and only going out for appointments or in a wheelchair), so I started LDN again and took it through until August.

    It improved me enough that I'm now partially housebound (I spend more time out of bed in the day and can go out once a week, as well as take my dog out sometimes). I will resume taking it when/if this improvement starts to slide back down again.

    I also found I do not need the full 4.5mg dose. I am okay on 1-1.5mg. I take it for 3 weeks, break for 2 or 3 days (miss 2-3 doses), resume taking it and repeat that cycle until I am no longer seeing improvements. The small break is to try to prolong how long I can take it before reaching a plateau of no more improvements.

    I should clarify that amongst other health problems, I also have autoimmune thyroid disease (for which I take natural dessicated thyroid). So I am not sure whether the LDN is working primarily on this condition or not... I have had M.E. since 1991 and AI thyroid disease since 2009, and LDN is the only thing that had ever touched my M.E. symptoms.
     
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  13. panckage

    panckage Senior Member

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    Thanks for following up @CantThink I found LDN worked amazing for about a month but then slowly lost its effect over a couple of weeks. I'm now experimenting to see how I can get the effect back
     
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  14. CantThink

    CantThink Senior Member

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    It's really frustrating isn't it. I hope you can get it to work for you again.
     
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  15. PatJ

    PatJ far and free I gaze

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    Here are some pointers to consider if LDN isn't working (they seem to cover lack of effect more than fading effect, but maybe there is some information that could help):
    When LDN isn't working.

    You can try pulsing. Take it every other day, or every couple of days. Or take for a month, stop for a week, take for another month. Or try varying the dose with each pulse (ie. 3mg one day, 4mg the next. Maybe it could prevent the body from adapting to a consistent dose, if adaptation is what is causing loss of effect.) One doctor uses split dosing, 1/2 in the morning, then 1/2 in the evening.
     
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  16. don60

    don60

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    This is exactly what I do. Once a drug passes from a solid to a liquid state, its shelf life can decrease dramatically. Therefore, do not make more than 50 ml of liquid Naltrexone at one time, store it in the refrigerator, and do not keep it for more than 2 months.
    [​IMG]
     
  17. debored13

    debored13 Senior Member

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    damn i've been keeping my naltrexone in the fridge for like 5 months, should i consider it useless now???
     
  18. PatJ

    PatJ far and free I gaze

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    It might not be useless, but it might be contaminated by bacteria etc. One reason for using distilled water, refrigeration, and 1-2 months max storage time is that micro-organisms can grow in the solution. I mix small batches based on a single Naltrexone tablet so that it doesn't sit for long in the fridge.
     
  19. debored13

    debored13 Senior Member

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    wow, I thought it would be ok in the fridge, especially since it isn't a solution that has sugar, I thought it wouldn't be that hospitable to bacteria growth. guess I'll throw it out and use the capsules I have to make volumetric solutions--a little less precise
     
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