i know that mast cells are throughout your body, but are they concentrated in gut & sinuses? My "allergies" are completely out of control... my eyes feel like they're going to fall out of my head, my brain fog is terrible, my sinuses, threat and lungs feel swollen and itchy I say "allergies" because it's allergy season, and my histamine symptoms are way worse.. however, I've had extensive allergy testing done (both blood and scratch) and it came up negative.... I tested high for tryptase, so it must be mast cells, right? Is it possible to have massive allergies and test negative because your immune system is too lame to make antibodies? Has anyone ever heard of this?