I have found that the only type of holiday I am really able to do now (and the only one on which my wife truly relaxes knowing I'm ok) is a cruise. Having had ME/CFS for 12/13 years, I think it's the perfect break for many people with our illness - for example ; - a cruise allows travel to beautiful places with a bed/cabin just minutes away for the most part. - you don't necessarily have to fly - and check-in/boarding usually takes minutes (rather than hours) from the point they unload your car or coach, and Assisted-Boarding is available for those requiring it. - most cruise companies offer dedicated restricted-diet chefs that ensure a much better/easier dining experience for those suffering food intolerances than is available in normal restaurants. - cost is very reasonable, with some cruises costing as little as £40 per night - amazing considering it's full board and great quality. - you can do as much (or as little) as you are able, and most things onboard are done on a very relaxed basis which allows you to recharge/rest in-between ports. I appreciate it can be incredibly difficult to go anywhere with ME/CFS, but are there any other vacations you think work well for our illness ? If so, why and what is it that makes it so ?