I've been on the Freddd protocol for seven weeks, and have had some nice changes: Gut much more stable Brainfog gone Sleep 2 hours less per night No more fatigue Gained 3 kg (good) Libido much higher Halved hydrocortisone dose to 10mg/day Better blood-sugar response (less knocked around by carbs) Improved motor skills, e.g. typing Better exercise tolerance My psoriasis faded, but I had to cut the LCF back after a crash, & it came back. I had some tolerable start-up effects (now mostly gone), and have had two bad crashes: caused by way too much LCF, & possibly too much m-folate. I cut back on everything after the crashes (especially those 2) and am now on: .5mg mB12 three times a day 200mcg m-folate three times a day 100mg LCF twice a day 10g AdoCbl once a week + base supps, potassium, etc What next? I'm very happy with this progress. But I could still use a better mood, no psoriasis, and to be more sociable. Do I increase, or just wait?