This is not related to anything I am currently experiencing, but I have been pondering on two main issues: Do other chronic illnesses show complete or substantial remissions? What could remissions, whether lasting an hour, a day, a week, a month or several years, tell us about our illness - an illness that has proven so resistant to permanent recovery for most of us? I've seen a few threads discussing remission, and there do seem to have been some attempts to make structured analyses of what remissions might mean, but haven't yet found any useful theories or conclusions, but then I haven't spent a lot of time searching. There was a very-promising looking one in 2010, but it seemed to end without resolution, and we have learned quite a lot since then. By remission I mean something more than improvement - I mean substantially-increased cognitive and physical function, plus improvement in sleep and mood, and decrease in or disappearance of pain, for those who suffer from these. The improvement must include significantly or completely improved resilience to exertion and other things that usually make things worse. The person should feel near-normal again. There should be no PEM. I am going to invite some of our resident scientists/doctors to hopefully contribute some expert ideas and knowledge. @Jonathan Edwards, @charles shepherd, @Butydoc Please invite others you can think of. Individual experiences will also be useful, including what might have led to remission.