Professor & patients' paper on the solvable biological challenge of ME/CFS: reader-friendly version
Simon McGrath provides a patient-friendly version of a peer-reviewed paper which highlights some of the most promising biomedical research on ME/CFS ...
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What makes CFS different from somatoform disorder

Discussion in 'General ME/CFS Discussion' started by bostjan01, Feb 7, 2018.

  1. femtosecond99

    femtosecond99 Senior Member

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    It is very well established that psychological stress causes significant alterations to the immune system, and that pain has a psychological aspect.
     
  2. femtosecond99

    femtosecond99 Senior Member

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    I suspect you won't accept any evidence. However it is very well established that stress causes bowel movements and diarrhea. This is very easy to demonstrate in the lab. You can probably even test it on yourself. Anyway, there's not really any doubt about this. By definition, IBS-D is an abnormal number of bowel movements, so therefore if you are under stress and that stress is sufficient to cause diarrhea, then IBS-D can be caused by stress. There are likely other factors at work as well, and IBS could be caused by a range of different things, but stress is definitely one of them. If you look at the major reviews on IBS, they say the same thing.
     
  3. femtosecond99

    femtosecond99 Senior Member

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    It was VO2max I was referring to, which didn't replicate earlier studies. Although you're right that peak workload did reduce in all 3 trials on day 2 (although only by 13%, which I don't think is sufficient to explain PEM). I used to think the repeat CPET might be a good biomarker, but now I'm not so sure. It certainly has promise, but we probably need some larger trials.
     
  4. Cinders66

    Cinders66 Senior Member

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    Pain has psychological aspect Really? According to you I gues. I dont think so. Let me tell you a story. My cousin had an FM/ME diagnosis with crippling pain being a key feature. Her GP pushed her to see a psychiatrist for her pain, she refused as saw no psychological relevance, the GP obsessed with the fact that she still lived at home and didn't socialise, the GP dismissed her terrible period pain as just another manifestation too. As it turns out she had endometriosis and is so scarred she can't have kids, her diagnosis was changed eventually to lupus and guess what, with that "respectable, proveable illness" all suggestion of seeing psychiatrists and blaming her illness on her abnormal social circumstances ended. She's now mananaged by an immunologist I think. When they find a cure for that autoimmune illness her pain will disappear. If stress exacerbates pain it really is just a secondary thing.

    Stress can affect the immune system and trigger IBS and exacerbate many physical illnessss /conditions - yes. So Stress is causing the NK T cell etc dysfunction in ME, unlikeky. So Stress is causing the immune FLARE - sore throats, aching etc during PEM in ME after physical exertion like taking a walk or shower or in my case moving in bed, nah. So Stress is causing illness like IBS - no it just irritates an already malfunctioning system. How about listening to pwME who will say stress exacerbates things and may have helped to develop the illness to start with but is not in the main a key perpetuator because generally people who are sick believe it or not try to take care of themselves .
     
    Art Vandelay likes this.
  5. Joh

    Joh Inactivist

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    Can you please give your sources for these claims?
     
  6. unicorn7

    unicorn7 Senior Member

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    Somatoform disorder doesn't exist.

    Psychological stress, just like every other stressor, plays a role in the development of literally every disease, from cancer to diabetes to infections. There are about hundreds of factors (diet, genes, stressors, infections, environment etc. etc.) that, all together, make you ill or not. The fact that psychological stress is one of those factors to put a dent in your immune system and make you just a little more vulnerable for an illnesss, doesn't say is plays a role in maintaining disease.

    The problem these days is that statistical preventative research is being extrapolated as being the same as curative medicine.
    Just because you have a smaller risk on getting disease when you eat a healthy diet, move throughout the day and keep your stress down, that doesn't say that you will never get a disease if you do that, or your disease is caused by one of those factors or that you can cure disease by having a healthy lifestyle and meditating all day.
     
    Cinders66 and pattismith like this.
  7. femtosecond99

    femtosecond99 Senior Member

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    Which particular one? This is all very well established stuff, so I didn't think it was necessary to post references, but I'm happy to post some if you're genuinely interested and not aware of this science.
     
  8. andyguitar

    andyguitar Senior Member

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    All depends what you mean by 'Psychological'. To my fairly simple mind everything is physical in origin. If not how could it exist?
     

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