This is the biggest reason I am sick of treating symptoms. Thanks for articulating it better then I could! Also, I'm sure there is a methylation block, but I am certain now that treating it directly isn't the only way this can be lifted. It's obviously int some of us it's more like a methylation supression than a self perpetuating block that must be lifted with supplements. This is why people are having success with recovering using treatments not including the methylation treatment.