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9th Invest in ME International ME Conference, 2014 - Part 1: Autoimmunity and ME
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what is C4A?

Discussion in 'Diagnostic Guidelines and Laboratory Testing' started by sarahg, Nov 9, 2009.

  1. floydguy

    floydguy Senior Member

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    I don't think it's totally clear yet what causes high C4a. Certainly, I would check for mold in the house. But it's not always just mold causing high levels. In my case, I lived in the desert in a tent for several months and my levels went higher. With high levels like yours, you can certainly conclude your immune system is either dysfunctional or being disturbed by something. But I am not sure you can conclude anything specific. Shoemaker would probably say that the fluctuation has to do with mold exposure and that may be occasionally be the case but I am not sure if anybody really knows in all cases. Mine have been as high as 67,000 but now are typically at 15,000. I haven't gotten them checked for a while. I don't think my insurance covers the test any more.
  2. mlccc2

    mlccc2

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    Thanks for your reply. When your C4a was at 67,000 did you have any symptoms? How about at 15,000? Any exposure to mold? Any symptoms now? I have numerous neurological problems that change all the time. We did have our house remediated for mold as one of our shower pans was leaking. I basically just feel lousy all the time. Doesn't help to have Epstein Barr virus either.
  3. mlccc2

    mlccc2

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    Anyone experienced several episodes of muscle twitching/leg cramps along with itchy skin, a sense of something crawling on you and your hands going numb? My hands are almost always ice cold for some reason and I have no history of poor circulation. Above symptoms are really pronounced when I attempt to lie down anywhere and frequently wake me up.
  4. mlccc2

    mlccc2

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    Anyone able to read Ignex Western Blot tests? I cannot get the ordering physician to interpret mine. Any help would be greatly appreciated!!

    Ignex panel results were as follows:



    (Lyme IgM Western Blot)

    IGENEX IGM RESULTS NEGATIVE
    CDC/NYS RESULTS NEGATIVE

    18kDa -
    **23-25 kDa -
    28kDa -
    30kDa -
    **31kDa -
    **34kDa -
    **39kDa -
    **41kDa IND
    45kDa -
    58kDa -
    66kDa -
    **83-93kDa -


    (Lyme IgG Western Blot)

    IGENEX IGG RESULTS NEGATIVE
    CDC/NYS RESULTS NEGATIVE

    18kDa -
    **23-25 kDa -
    28kDa -
    30kDa -
    **31kDa -
    **34kDa IND
    **39kDa IND
    **41kDa ++
    45kDa -
    58kDa -
    66kDa -
    **83-93kDa -

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