I've found I need a pretty high daily dose of B6 (1000mg time released B6 & 100mg P5P) to keep deficiency symptoms at bay. Even still there are times I could use a bit more particularly of P5P, but I don't go above 100mg a day.
Prior experience leads me to believe though that whenever there is an abnormally high dose of something needed, it's very likely it's due to an inefficiency somewhere.
I switched to a low oxalate diet 3-4 months ago, which should help to some degree (removing oxalates made a noticeable improvement in my zinc levels). I also got tested for Pyrrole Disorder and came back negative, but even after that, I am still at the above dose.
Any suggestions on where else I might look to get better efficiency out of my B6?
FWIW - This doctor mentions that Lysine deficiency can effect B6 function, but I can't find anywhere else that confirms that comment. http://www.beyondmthfr.com/side-high-oxalates-problems-sulfate-b6-gut-methylation/
Prior experience leads me to believe though that whenever there is an abnormally high dose of something needed, it's very likely it's due to an inefficiency somewhere.
I switched to a low oxalate diet 3-4 months ago, which should help to some degree (removing oxalates made a noticeable improvement in my zinc levels). I also got tested for Pyrrole Disorder and came back negative, but even after that, I am still at the above dose.
Any suggestions on where else I might look to get better efficiency out of my B6?
FWIW - This doctor mentions that Lysine deficiency can effect B6 function, but I can't find anywhere else that confirms that comment. http://www.beyondmthfr.com/side-high-oxalates-problems-sulfate-b6-gut-methylation/
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