James C Coyne is a bit of an interesting psychologist - a bit of a renegade as he asks searching questions of psychology. This is particular piece I'm referring to: so not new. This touches on some issues I explored in my paper about trying to make sure similar standards are applied to nonpharmacological therapies as pharmacological therapies e.g. and He makes some other interesting observations also on the comparison between antidepressants and psychotherapies for depression.* *Note: my main interest in this is not to do with the specifics of the debate about how to treat depression, but just general issues for when pharmacological and non-pharmacological therapies (such as CBT and GET for ME/CFS) are compared.