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What has helped more with your sleep?

Discussion in 'General ME/CFS Discussion' started by Beyond, Nov 1, 2013.

  1. WoolPippi

    WoolPippi Senior Member

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    A little update: progesteron pill keeps me asleep. 100mg on a regular day, 200mg on day 21-28.

    However: excess Folinic Acid overrules this and keeps me awake for 3 to 4 hours. Worse than ever.

    I think firing up the Methylation Cycle too much gets the Sympathetic Nervous System all excited. Excess noradrenaline at night. More balanced Folinic Acid allowed me to sleep through again.
    (2mg Folinic Acid with 1200mg mB12 is maximum for me)
     
    Beyond likes this.
  2. teefy

    teefy

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    At night I take:
    1. Gabapentin 300 mg
    2. Zolpidem 15 mg
    3. Magnesium Sulfate injection 2 ml
    plus:
    4. NAC 1000 mg
    5. D-Ribose 4-5 g in warm milk
    The NAC and D-Ribose make little perceivable impact, although I think they help a bit.

    This is where I am just now and it's the best combo I've had for a while.

    Agomelatine 50 mg helps occasionally to give the Zolpidem a break. Taurine injections 2 ml also help, but are expensive. Baclofen 30 mg also helps, but I don't combine it with the Gabapentin.

    Re-timer glasses on getting up also help, but I can only tolerate them intermittently, and not during bad episodes.

    It's a good day for me just to be able to write this!
     
    maryb and Beyond like this.
  3. Beyond

    Beyond 10% of discount in iHerb!--> PEZ915

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    That´s awful. You don´t know how far you can fall until you do. This life and our bodies it seems were designed to be able to create and experience amazing depths of suffering. Heh heh not very positive uh? But who can say it is false!! I can write in the forums even the worst days, for me a good day is one I can go to the beach or shopping and feel slightly hopeful about the future.

    Thanks for your input. I am making a list of things I want to try for sleep in a Word file, medications and supplements. I have been reading some abstracts about inflammatory bowel disease and sleep disturbances and undoubtely bad sleep both causes and is caused by intestinal inflammation. Fighting the sleep dysfunction and intestinal inflammation is the way to go for my case at this moment and probably for many others. So I need to carry these lists to the docs and be clear about what I want: try sleep meds for my severely f*#ked up sleep!
     
    MeSci likes this.
  4. Little Bluestem

    Little Bluestem Senescent on the Illinois prairie, USA

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    How much ashwagandha do you take, @Digby9 ?
     
    Beyond likes this.
  5. Digby9

    Digby9

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    Full disclosure on the ashwagandha is that I am taking the Life Extension product, "Enhanced Natural Sleep." It has 200 mg of Ashwagandha and some bio active milk peptide. The latter doesn't seem to do much of anything by itself but the combination helps. I think the N-acetyl-cysteine and melatonin help too but the thing that has finally made a lasting (over a month) difference is the combination of blue blocking glasses at night and bright light therapy in the AM.
     
    Little Bluestem and Beyond like this.
  6. Beyond

    Beyond 10% of discount in iHerb!--> PEZ915

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    Those glasses, I have to try them at last!
     
  7. madietodd

    madietodd Senior Member

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    Which light box do you use?
     
  8. Digby9

    Digby9

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    Little Bluestem and madietodd like this.
  9. Iquitos

    Iquitos Senior Member

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    Beyond likes this.
  10. Beyond

    Beyond 10% of discount in iHerb!--> PEZ915

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    I have interest in cannabis oil, how much is it costing you and where are you buying it?
     
  11. Iquitos

    Iquitos Senior Member

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    Use the link above for a thread about it. I'm getting mine from Amazon. $40/1oz, free shipping, Cibdex CBD Drops, 80 "servings" at 15 drops per day.

    They ship to some other countries (I'm in the US) but haven't checked about Spain. Hip, in the CBD thread, says Amazon ships it to UK.
     
    Last edited: Jan 26, 2014
  12. Digby9

    Digby9

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    I'm interested in the CBD drops also. They are supposed to be good for inflammation, pain and sleep. I've heard about the Cibdex drops but heard that a much larger dose (4 to 6 times) was necessary, making it too expensive. I'll check out the other thread. Thanks.
     
  13. Iquitos

    Iquitos Senior Member

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    Yes, I'm finding that to be at least partially true. I've tried the 15 drop dose and it's not enough. 30 drops, or double the dose, seems to work for me, though. And the other brand out there, Dew Drops, (I think) has the same amount of cannabidiol in it.

    I only chose the Cibdex because of internet gossip purportedly coming from Dixie's former scientific director, claiming Dixie, the maker of Dew Drops, had dirty and other bad practices in manufacture. This is third or fourth hand "information" but the price is the same so I picked Cibdex.
     
  14. WoolPippi

    WoolPippi Senior Member

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    I took N-A-C for 2 days and went straight back to lying awake, even with progesterone pill on board.

    Richvank says that N-Acetyl-Cysteine is welcome to the liver because it needs the cysteine to make glutathione. But NAC can shake loose mercury from various body tissues and lets it bounce around the brain. My 600 mcg clearly was too much.

    I find that I need to keep my brain chemistry uneventful or I go straight back to lying awake. NAC does this, too much folinic acid does this, Zinc/Copper imbalance does this, stress or anger during the day does this, garlic does it, nutmeg too.

    Man, I'd like a new batch of spaghetti in my skull please. Hold the sauce.
     
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  15. Izola

    Izola Senior Member

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    I think I could use some of that. Iz
     
  16. Izola

    Izola Senior Member

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    I think if my Doctor tested my cortisol she would faint at the results. Iz
     
  17. Izola

    Izola Senior Member

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    I would prefer the dependency over lack of sufficient sleep. Sleep is when the brain heals and when the liver fixes things. Iz
     
    Iquitos, Beyond and heapsreal like this.
  18. WoolPippi

    WoolPippi Senior Member

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    going to GP tomorrow to get referral for a neurological sleep test. I've had it, I want someone to look at my neurotransmitters. And then wack me over the head with the tea kettle.

    Prog. pil only seems to work in the first half of the cycle and only when on moderately methylation protocol.
     
    Izola likes this.
  19. MeSci

    MeSci ME/CFS since 1995; activity level 6

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    Sorry to hear this. Good luck with finding a solution.
     
  20. Beyond

    Beyond 10% of discount in iHerb!--> PEZ915

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    I got my most recent sleep "stack" as bodybuilders and supplement freaks (lol) call it. I hope I can come back here and report significant relief!!

    I got fed up of overdosing in melatonin just to get a rather crappy sleep which was letting me have some functionality. It wasn´t worth because taking large quantities of an hormone over time like melatonin surely is no good, especially since I am young and should be producing it.
     

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