Professor & patients' paper on the solvable biological challenge of ME/CFS: reader-friendly version
Simon McGrath provides a patient-friendly version of a peer-reviewed paper which highlights some of the most promising biomedical research on ME/CFS ...
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What Fixed/Aided Your Brain Fog?

Discussion in 'Cognition' started by MAF14, Feb 29, 2016.

  1. hamsterman

    hamsterman Senior Member

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    Hmm.. interesting. how much did you take?
     
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  2. Wonko

    Wonko Senior Member

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    The other side.
    At that time I think I was taking 400 a day, with the odd accidental increase to 600 (my organisational abilities re supplements, or anything that needs taking more than once a day, with food, empty stomach etc was/is a bit iffy)
     
    Last edited: Oct 6, 2017
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  3. Wishful

    Wishful Senior Member

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    I tried CoQ10. I didn't notice any benefits. Apigenin did reduce my brainfog enough that I bought more, but I'm not sure if it's still having any beneficial effects for me. I think apigenin is one of those things that worked only for a short time and then stops working ever after. ME/CFS just seems to keep adapting to keep me miserable.
     
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  4. JaimeS

    JaimeS Senior Member

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    And how much did you take of CoQ10 and Apigenin? :)
     
  5. Wishful

    Wishful Senior Member

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    I can't remember the CoQ10 trial; probably the recommended daily amount followed by double the amount for a while. I didn't try mega-dosage for long periods though.

    Apigenin gave a slight--but noticeable--reduction in brainfog at 50 mg/day. Increasing the amount didn't seem to help more. The improvement showed up fairly quickly though; I think I noticed the improvement the next day.

    Of the drugs/supplements I've tried for ME/CFS symptoms, most work within 24 hrs. Prednisone was an exception, since it took 5 days to start working the first time, two days the second time, and never had any effect after those two trials.
     
  6. JaimeS

    JaimeS Senior Member

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    Still not 'mega' -- CoQ10 dosages that are safe run the gamut.

    You might get 100mg as a 'normal' dose, or 200mg. Double that is still 6 - 12 times less than what I take on an average day (2.5-g). Look up the dosages used in multiple sclerosis and you'll see what a high, but still safe, dosage of CoQ10 is.

    I agree. I think there's a subset of patients where metabolism is either very, very slow -- or their digestive systems are screwy enough that they're not absorbing, much. But I'm an easy-reactor, which is the other half of us. I usually notice almost immediately if something is going to help or harm.

    But the dose does matter; and in the case of CoQ10, the form and the brand also seems to matter.

    -J
     

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