Hi Soulfeast, 60 mg of Ab12? Thats about 7 sublinguals in one day? This is a one time dose? That is 6 x 10mg-adb12 from Source Naturals. I use the mass of adb12 itself, not conversion to the number of molecules of cyanocbl equivalence which is a fiction since anything beyond 125mcg of cyanocbl is fiction anyway. After there is NO PERCEPTABLE effect from taking a single 10mg adb12 and all the body startup for adb12 is finished, then one tries the 50-60mg adb12 test. If there is an effect likely it will only happen once as it birngs the CNS up to equilibrium. I do it once a week to maintain that equilibrium. ALS and Parkinson's and possibly others have a specific indicator for low adb12 of MMA in the CSF and it is thought that it takes a couple of decades of malfunctioning neurological mitos for the damage to develop. Also, I feel better, have more energy, my brain works better and better moods and better sex. All good reasons to try it. If there is no effect he first time, according to my hypothesis they are not short of it in the CNS. The effect is small and not terribly noticable and gets lost in the much larger body effects if equilibrium isn't reached in the body first. The mb12 and adb12 effects of the 50mg test are quite independent and different. I can't vouce for adding that much sodium salt to ones intake. Somebody also said that it interfers wioth the potassium. I don't know.