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What does a gene Mutation of Mthfr have to do with mythl

Discussion in 'Detox: Methylation; B12; Glutathione; Chelation' started by place, Apr 25, 2012.

  1. place

    place Be Strong!

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    I had some gene testing a couple years back for something other than ME and I had a mutation of C677t. I was just reviewing some of my past tests and found this result with a paragraph under it talking about how it helps the body with folate????

    Has anyone heard of this???
  2. nanonug

    nanonug Senior Member

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    Virginia, USA
    This has been talked about ad nauseum in this forum. Just do a search for MTHFR. The bottom line is that a reduced capability to convert methylenetetrahydrofolate to methyltetrahydrofolate significant impairs the methylation cycle. Folic acid becomes "poison" and the need therefore arises to supplement with methylfolate.

    By the way, are you hetero or homozygous for the C677T mutation?
  3. place

    place Be Strong!

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    hummmmmmmm

    homo...

    I am having infertility issues and a Dr. out in Cali ran a bunch of tests... this was one of them.

    Things are starting to click for me as far as possible solutions/problems.

    That dr prescribed folic acid and it just made me sick.... I thought is was due to being made with yeast (I can't handle any yeast or it makes sick)

    And the plot thicken..... I think Rich is really on to something. Im going to start calling him the Wizard!



    Thanks for your insight! Very much appreciated!!

    place
  4. nanonug

    nanonug Senior Member

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    OK, if you are homozygous for the MTHFR C677T polymorphism then you definitely need to stop taking folic acid and start taking methylfolate, especially if you want to get pregnant.

    Yep, Rich is one of the smartest dudes around!
  5. hixxy

    hixxy Woof woof

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    Russell Island, Australia

    LOL. Gotta love medical ignorance If a doctor can't understand a test why is he running it??? Folic acid is poison for you with that mutation
  6. greenshots

    greenshots Senior Member

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    That seems to be the way of things everywhere these days. Occasionally, they know why they're doing something but I think most of the time they just don't! You have to get real lucky to get a doc who gets this stuff without trying to kill you in the process! I ain't EVER leaving my California dream doc!
    Angela
  7. ukxmrv

    ukxmrv Senior Member

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    Hi Place,

    I was tested for the MTHFR mutation in the same way during investigations for infertility. At that time there were internet groups set up for patients doing the same thing. What form of folate was your doctor using? At the time I looked at this Folapro was being used by most of the patients on these groups.

    Hope all this info helps you.

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