I've been on Fredd's protocol for a month (I was on Rich's for 2 months before that with no success) and things have been going ok. During the past few days my appetite has decreased, especially in the morning. Yesterday I could not finish breakfast because I felt like I would vomit if I took another bite. That never happens to me. I was just eating oatmeal with a banana. What could cause it? The basics of my supplementation are as follows: I am taking all the basic cofactors. My methylfolate doses have increased rapidly -- starting with 1200mcg and doubling every week (2400, 4800, and now 10,000). My potassium intake has remained constant at 1500mg. My MeB12 dose has increased from 2000mcg to 10,000mcg. I started AdB12 at 10,000mcg 1x/week and increased it by 10,000mcg each week so now I'm up to 40,000mcg. This may be too much. I seem to feel really good on the day I take it, but my emotions go all out of whack the next day (and for a few days afterward). I phased in LCF 2 weeks ago. I tried going over 125mg but it was too much so I have been staying at that dose.