@garyfritz You seem to have benefitted greatly from the adoB12, as well as the MeB12, so I thought I'd ask if you know of any other threads that deal specifically with it.
I've only taken it a half a dozen times and each time, the reaction was pretty big--initial nervousness, breathlessness and shakiness I can get through, as well as the tiredness now that seems to follow for a while. My two recent attempts:
1. three days in a row at 1/8th tablet in the a.m.; 4mg MeB12 and 800mcg folate p.m. I slept better the first two nights, then was overwrought, sleepless and had to take niacin the third night. Increasing folate deficiency symptoms and higher need for potassium. (Maybe following this pattern I ought to take the adoB12 only every other day or every third day and titrate up from there...)
2. one day before Christmas I took another 1/8 tablet in the a.m. along with 3mg MeB12 and 800mcg folate; in the afternoon I repeated the 3mgMeB12 and 800mcg folate. I had not only anxiety and breathlessness much of the day, but also increasing inflammation, need for folate. I slept only 3-4 hours that night. My need for potassium spiked over that day and the next--from about 1,200/day to 1,500-2,000. (clearly, this was methylation overkill!)
I've kept potassium levels high as I've tried to re-stabilize. Since major inflammation is part of my struggle, I'm sure the adoB12 is good for me and that I sorely need it. I'm thinking on my next attempt, I'll take it alone in the morning, followed by the usual MeB12 and folate doses in the afternoon.
Or possibly just stopping everything and just taking the adoB12 alone to see exactly what its particulate needs are and to bring it up to some sort of sufficiency
This thread has also reminded me that it's possible that I need to treat my MAO++ further--more magnesium (now about 500 mg citrate+malate) and more B2 than I'm getting in my daily (roughly 25mg of r-5-p, I think).
It's also interesting to me that you noticed no difference from the lithium; I've got the TCN++ snp and have tried it only once. It seemed to give me day-long indigestion. I haven't gotten around to trying it again.
I can only put myself through so many experiments before I need a break!