For a moment, let's say that the XMRV routes of transmission are the same as the HIV routes. I am wondering if there are many CFSers who would object because they couldn't possibly have been infected by those routes. I know there are many of you who did not have sex before you got sick. But what about: 1) getting stuck with a needle that may have had someone else's blood, or anything else similar. I was remembering that when I was a child, we would do that "blood brothers" thing where my friend and I would have little paper cuts or something and we'd try to get our blood to contact. Also something like, if you picked up one of those needles that diabetics use. 2) could your mother has given it to you? HIV transmits "during pregnancy, at birth and through breastfeeding" 3) transfusion like I said... but skin grafts, organ donation, artificial insemination also count 4) unprotected sex... also if you had protected sex, maybe the barrier broke or was faulty? I think sometimes we don't realize we had blood contact because... some random examples that pop into my head are: Maybe I scraped my knee and bled a lot and then a family friend was helping me and they didn't think about the little cut on their hand. Or I was helping a kid with an injury. Also because I think sometimes the broken skin is a lot less obvious. We were just itchy from a minor rash/bug bite and the skin is actually broken even though it's not exactly bleeding.