I apologize for those severely ill. My post is for those who are somewhat able to do exercise. I haven't been sick long, three years, so I am still learning how to manage this illness. So far it took me about 1 1/2 years to stop having PEM. I attribute it to taking Nimodipine, which I started in march at a very low dose. In may I had my last 4-5 days of PEM. No more since. That's the most improvement I have had, and it is a lot. My energy is still low and all my dreaded symptoms reappear when I Have stress and or lack of sleep. I am trying to go back to work before winter, so I started walking or biking (16 km/h) for about 50 minutes, about 5 times per week. After 6-7 weeks of that and it's going fairly well, but not perfect, I figure I have to do more if I want to be able to do my 12 hour long day when I work. So I am adding a short session to the gym to the walk, 4-5 times a week. But, and it's a big " but ", my main symptom these days is muscle weakness in all my body, even my hand, mouth, feet, everywhere. Mostly the legs, of course, they have the biggest muscles. I used to do weight lifting when I wasn't sick, so this is something I know well. I am using my heart monitor to stay under my anaerobic threshold. So here is my question : knowing my muscle weakness has not improved at all in the past 18 months, am I at risk of getting worse by doing gym work ? Or is this muscle weakness just something I have to learn to live with and exercise will be of benefit, because I am improving my fitness level ? I should also say I Have no pain, other than the pain from sitting too much... And I am a woman, if it matters. Thanks for your input !