I was talking to someone with EDS recently, and they said they were an encephalitis survivor. I wonder how common that is in EDS. Lipkin identified an ME subgroup, which he labelled Atypical ME, in which there is a stable cytokine profile. This group contains lots of encephalitis survivors. I wonder how common that is too. I am also an encephalitis survivor. If EDS compromises the blood brain barrier and so pathogens can more easily cross to the brain then encephalitis should be more common. This may be a powerful ME trigger.