Hi Beyond, Thanks for the follow up. Yes, adrenal dysfunction definitely seems to be a factor in all of this. I also found out that my levels of the Anti-Diuretic Hormone (ADH or Arginine Vasopressin) are also very low. I suspect that it is at least partly due to a high fluid intake during the day. I've previously reduced the amount of water and fluids I'm drinking daily, and have noticed that I'm waking up fewer times during the night for a bathroom trip. However, I also still suspect that there may be a metabolic and/or methylation component to the low ADH levels. Someone more knowledgeable than I in these matters commented that Arginine levels can be related to methylation. They said that it reacts with BH4 in order to make Nitric Oxide, and that BH4 synthesis can become compromised in people with methylation issues. They also suspected that I could be low in SAM-e as well which is responsible for Creatine production which also affects water storage. I'm currently in the early stages of a methylation protocol, have recently started mild thyroid hormone support, and have been working on correcting the adrenal dysfunction for a couple of months now.