1. Patients launch a $1.27 million crowdfunding campaign for ME/CFS gut microbiome study.
    Check out the website, Facebook and Twitter. Join in donate and spread the word!
New Exercise Study Brings Both Illumination and Questions
Simon McGrath looks at new objective evidence of abnormal response to exercise in ME/CFS patients, and the questions that researchers are still trying to answer ...
Discuss the article on the Forums.

Vitamin C Dosing and Megadosing

Discussion in 'General Treatment' started by arx, Dec 19, 2012.

  1. arx

    arx Senior Member

    Messages:
    525
    Likes:
    134
    Hi,

    I just wanted a view on how Vitamin C has helped people. There are people who are helped by large doses of this vitamin and there are those who are not.
    I have also read that :A cancer-causing mechanism of hexavalent chromium may be triggered by vitamin C.
    Reading things like this, I don't feel like going in for a megadose trial.

    I know Vitamin C is not really useful in CFS and it might be a cofactor in many of the protocols,but if you have anything to share related to Vitamin C, please do.

    Thanks.
  2. lnester7

    lnester7 Seven

    Messages:
    1,161
    Likes:
    1,029
    USA
    I see Dr Rey @ Klimas and she has me on 2,000mg a day of Vit C (with CoQ10, Fish oil) they call it cell food. I am not sure what is doing but the protocol overall is helping me.
  3. caledonia

    caledonia

    Messages:
    2,729
    Likes:
    1,318
    Cincinnati, OH, USA
    Rich Vank says no more than 2 grams (2000 mg) of vitamin C for methylation purposes. In general, you would want to spread this out in several doses throughout the day, not all at once. Ben Lynch says no more than I think 500mg per dose (also for methylation purposes).
  4. Rand56

    Rand56 Senior Member

    Messages:
    488
    Likes:
    173
    Myrtle Beach, SC
    Personally, I feel better when I limit myself to no more than 500 mg's of supplemental C per day. I take it as sodium ascorbate.
  5. ggingues

    ggingues $10 gift code at iHerb GAS343 of $40

    Messages:
    3,917
    Likes:
    783
    Concord, NH
    I take 4 to 5 grams of Vitamin C a day, in 1 gram doses 2 to 3 hours apart.

    GG
  6. Sasha

    Sasha Fine, thank you

    Messages:
    7,555
    Likes:
    5,579
    UK
    I'm currently on 2g vit C per day, not prescribed by anyone. I found it has prevented my getting burst blood vessels in my eyes when I sneeze hard - this used to happen to me all the time and I read that vit C strengthens the blood vessels and is recommended as a remedy for this.

    During my first (7 years confined to bed) bout of ME, I was under the care of a doctor who wanted me to slowly increase my dose of Vit C until it gave me diarrhoea and then cut back but 10%, which led to my taking a dose of 45g (that's not a typo) per day. I was on that for quite some time - months at least - and it didn't do a thing.
  7. adreno

    adreno 3% neanderthal

    Messages:
    2,187
    Likes:
    1,253
    Tundras of Europa
    I take about 4g daily. Less than that, and I start to get gum inflammation.
  8. taniaaust1

    taniaaust1 Senior Member

    Messages:
    7,726
    Likes:
    4,585
    Sth Australia
    I myself find vitamin C helpful for the sniffy nose I wake up with that I sometimes get (allergy related I think..eg dust mite). 2g of Vitamin C in the morning seems to help to get rid of that symptom in my case

    I also find Vit C helpful if Im coming down with a rare cold (I say rare as I rarely do get them) but I find that taking Vit C as soon as I start to get cold symptoms tends to stop further development. In that situation I usually take 2g morning and 2g night.

    So one can say for me that I tend to take 2-4g per day when Im taking C (6g at the most if Ive gone to taking it 3 times daily due to catching flu/cold). I only usually take it for the above things.
    SickOfSickness likes this.
  9. dannybex

    dannybex Senior Member

    Messages:
    2,160
    Likes:
    508
    Seattle
    Yes, I read the same thing. Lynch says that more than 500mgs will interfere with methyl-b12.
  10. adreno

    adreno 3% neanderthal

    Messages:
    2,187
    Likes:
    1,253
    Tundras of Europa
    Right, but if you take it 30 min after the mb12 it won't interfere.
  11. Sushi

    Sushi Moderator and Senior Member Albuquerque

    Messages:
    6,415
    Likes:
    5,164
    Albuquerque
    And Rich also used to say (this was a few years ago--2008--, I don't know if his opinion changed later) that bowel-tolerance doses would help augment glutathione levels.



    taniaaust1 likes this.
  12. AFCFS

    AFCFS Senior Member

    Messages:
    312
    Likes:
    243
    NC
  13. dannybex

    dannybex Senior Member

    Messages:
    2,160
    Likes:
    508
    Seattle
    Do you have a source for that Adreno? It just seems like it would take longer for the mb12 to do it's thing...???
  14. adreno

    adreno 3% neanderthal

    Messages:
    2,187
    Likes:
    1,253
    Tundras of Europa
    Methylcobalamin has a very short half-life, about 5 mins.

    Your own source, Lynch says you should take vitamin C 20-30 minutes after the mb12:
    http://mthfr.net/mthfr-c677t-mutation-basic-protocol/2012/02/24/
  15. dannybex

    dannybex Senior Member

    Messages:
    2,160
    Likes:
    508
    Seattle
    Thanks Adreno. :)
  16. AFCFS

    AFCFS Senior Member

    Messages:
    312
    Likes:
    243
    NC

See more popular forum discussions.

Share This Page