Hello all. I am new to this CFS/ME world but I think it fits more closely to what I am dealing with. I started off 4 plus years ago with shoulder blade pain, neck pain,, rigidity (flu-like fatigue) and a tremor. The tremor got all of the attention and I was boxed in with a label right away. Parkinson's... not Parkinsonism which is a mimicry of the classic lack of dopamine. I tit-rated up and down with the max/min dosage of Sinemet. I tried Rytary which is a combo slow/fast release of Ldopa. I switched to Mucuna to play with dosages and stay away from carbidopa (it depletes vitamin B6). What I came away with, if I took away the tremor, it would put me right in with CFS/ME. Pain, fatigue, depression, flu-like all day malaise. My tremor seems to be more controlled now with an anti-inflammatory. So that leads me to believe that I have Viral Parkinsonism (or HSV-1 Encephalitis). That is self-diagnosed at this point. They say it's quite rare but it does exist. The flu pandemic of 1918/1919 had a lot of accounts. I have also been working with a functional medicine doctor. We tested for viruses. I have active EBV, CMV, HSV-1, HHV-6. I have since been working with another doctor who is familiar with CFS/Fibro as he has dealt with it himself for 30 years. I am now taking valacyclovir, L-lysine, LDN, Baicailin... and a bunch of herbal immune support and anti-virals. After a few good days here and there for two months, I have been blessed with a 5 day stretch of feeling pretty good. My questions for this group: I know that the Valtrex works on EBV. My doc doesn't prescribe anything really for CMV or HHV-6, should I be proactive and try to get something in addition, like Valcyte? I have not been tested for enteroviruses.. should I or just add Oxymatrine and assume that I have those as well? Why don't I see any info on intravenous acyclovir? I feel this thing in my CNS and brain for that matter. I am Mr. Doom and Gloom when this thing flares up and when I have a handle on it, it seems like I forget about the bad. I swear I could feel this thing replicate on daily and 4-5 day patterns. The treatment for acute encephalitis is intravenous, this seems like the same except low grade infection...Has this been tried with any success?