Additional information VIP sent that may be helpful. (I don't see this listed on their site but perhaps there is a hidden button I have yet to discover.)
Questions and Answers regarding XMRV testing
The XMRV PCR/culture test and the XMRV serology test offered by VIP Dx use methods that will detect all known human MLV viruses
Q: Why is VIP Dx testing for XMRV different from other commercial tests presently being offered?
A: XMRV testing at VIP Dx uses the same methods which were published in the Lombardi et al. October 2009 issue of Science. Our methods require the collection and appropriate testing of 20 mL of whole blood. While this process is very time consuming and labor intensive, we have found that it dramatically reduces the rate of false negative results. For this reason, the cost of testing and the time to report results for XMRV by PCR/culture is greater than that of a standard PCR test.
Q: How long does it take to get my XMRV culture results?
A: In order to complete the full testing process and issue an approved results report takes approximately 5 to 6 weeks for PCR/culture tests. This period of time is required to grow the cells for virus culture analysis. Due to the large volume of test requests received, we currently have a longer time to process the approved results.
Q: Does a negative result definitively mean that I am not infected?
A: Although we strive to offer the most sensitive test available, XMRV can be present at a very low copy number and may be below the limit of detection at the time your sample was tested. Re-testing is a decision for you and your physician or health care professional to discuss and determine the best course of action. We do not recommend re-testing by PCR/culture for 3 to 6 months. You can test by serology in conjunction with PCR/Culture.
Q: Is it possible to have a positive result at one point in and a negative result at a later time?
A: Although retroviruses are integrated into the cellular DNA and are considered life-long infections, it is possible that your immune system may hold the virus to a level below the limit of detection from time to time. Presently, the life- cycle of the virus is unknown. If you receive a positive result at any time it is unnecessary to do retesting until more is known about XMRV.
Q: What is the turn-around time for the XMRV serology (antibody screen) test?
A: Typical turn-around time is 2 to 3 weeks.
Q: Should I stop taking antiviral medications prior to testing?
A: Medications can reduce the viral load to such a low copy that it cannot be detected by PCR/culture. The serology test is less sensitive to antiviral medications. CONSULT with your physician regarding your current medications and/or treatments and when you should proceed with your testing.
Q. Will the serology test replace the culture test?
Each test method will be offered as an individual test. Both tests can be ordered at a discounted price. Please refer to information in Q&A below.
Q. How will serology results be reported?
A. Results will be reported as either positive or non-detected (same as the PCR/culture). A positive result indicates that you have antibodies to the XMRV virus.
Q. How do I get a test kit for either or both types of testing?
A. Kits may be requested at
info@vipdx.com or by calling Client Relations at 775.-351-1890. You will need to complete a kit order form either by answering questions over the phone or downloading the form off the website and sending it to us by fax or postal service. There is a $65.00 kit deposit fee. Kit fees are not reimbursable by Medicare. Please see payment information below.
Q. What other tests does VIP Dx offer that compliment the XMRV testing?
A. VIP Dx offers various clinical tests for neuro-immune testing. Please refer to our test menu and test requisition for more information.
Q. Who gets my results? Can I have a copy of my results?
A. Results are faxed to the ordering physician/clinician. A patient can receive a copy of their results after they sign a release. A request for Authorization for Release of Results can be obtained by calling Client Relations after you send in your sample. Each request may take up to two weeks to process after results are reported to your physician. Patients can also request a copy of their results from their own physician.
Q. What if my doctor does not understand the results?
A. We will be happy to set up a conference call appointment with our consulting scientist and your physician. Have your physician call our office to schedule a scientific conference appointment.
Q. What is the difference between the two types of XMRV tests?
A. Serology detects antibodies to XMRV indicating previous immune response. PCR/Culture detects actual viral nucleic acid present in whole blood regardless of immune response.
Q. How much does each test cost? What is the price for both tests?
A. The PCR /culture test is individually available for $450.
The serology test is individually available for $249.
You can order both types of XMRV testing at a discounted price of $549.
Q. Is one test method recommended over another?
A. Certain immune dysfunctions may cause your immune system not to develop an antibody response to XMRV. It is also possible to test negative by PCR/culture if the virus is at such a low copy that it cannot be detected.
Therefore, it is recommended to have both the PCR/culture and the serology tests.
Retroviruses like XMRV are considered life-long infections. Future advances in technology and medicine may improve the quality of life for those infected with XMRV. There is still much to learn about this retrovirus and possible treatments. Research is on-going.
ADVICE to PATIENTS receiving a copy of their results: Do not take any action or begin any treatment without first discussing your clinical laboratory results with your physician. Medical expertise is required for interpretation of laboratory results.
VIP Dx is committed to excellence in quality, service and accuracy and no result will be reported before it has passed our quality assurance guidelines.
Client Service Hours: 9:00 a.m. 4:30 p.m. PST
Marguerite Ross, Director
Marketing & Client Relations
VIP Dx / RedLabs
5625 Fox Ave - Rm 369
Reno, NV 89506
775-351-1890
Fax: 775-682-8517
www.vipdx.com