New era for ME/CFS research as top cytokine study attracts media headlines
The immune systems of patients who have recently developed ME/CFS look markedly different from those who have been ill for much longer, according to a major new study from Drs. Ian Lipkin and Mady Hornig at Columbia University. This shift in immune function hadn’t been seen before.
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Viagra and multiple sclerosis in animals--off-topic. but interesting

Discussion in 'Multiple Sclerosis' started by richvank, May 23, 2011.

  1. richvank

    richvank Senior Member

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    Hi, all.

    I think this is really interesting. Seems to help with MS symptoms in animals. And imagine the side benefits! :D

    Rich

    Viagra reduces MS symptoms in animals
    Published: May 21, 2011 at 1:14 PM

    BARCELONA, Spain, May 21 (UPI) -- Multiple sclerosis symptoms in animals with the disease were drastically reduced by the sexual dysfunction drug Viagra, researchers in Spain say.

    The study, published in Acta Neuropathologica, showed a practically complete recovery occurred in 50 percent of the animals after eight days of treatment of the drug normally used in the treatment of erectile dysfunction.

    Drs. Agustina Garci and Juan Hidalgo of the Universitat Autonoma de Barcelona studied the effects of a treatment using sildenafil -- sold under the brand name Viagra -- in an animal model of multiple sclerosis.

    If given shortly after disease onset, the scientists say they observed the drug reduced the infiltration of inflammatory cells into the white matter of the spinal cord, reducing damage to the nerve cell's axon and facilitating myelin repair.

    Multiple sclerosis is caused by the loss of myelin sheaths around the axons -- a long, slender projection of a nerve cell that conducts electrical impulses away from the neuron's cell body -- affecting the ability of neurons to communicate and neurodegeneration in different areas of the central nervous system. There is currently no cure for the disease, but some drugs help fighting symptoms, the researchers say.


    Read more: http://www.upi.com/Health_News/2011...-in-animals/UPI-93231305998062/#ixzz1NBzIiQKi
     
  2. FancyMyBlood

    FancyMyBlood Senior Member

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  3. richvank

    richvank Senior Member

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    Hi, Fancy.

    I don't know, but I guess I would not be very optimistic that Viagra would help with most cases of ME/CFS, because of the low total blood volume frequently found in this disorder. Dilating the blood vessels will likely make it more difficult to get enough blood flow to the brain, especially when upright.

    Best regards,

    Rich
     
  4. Tammie

    Tammie Senior Member

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    Woodridge, IL
    quite interesting, but it sounds like it would be a disaster for anyone with orthostatic intolerance
     

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