The power and pitfalls of omics part 2: epigenomics, transcriptomics and ME/CFS
Simon McGrath concludes his blog about the remarkable Prof George Davey Smith's smart ideas for understanding diseases, which may soon be applied to ME/CFS.
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Very unsettled with constant brain firing

Discussion in 'Cognition' started by Zuriel, Jan 6, 2012.

  1. Zuriel

    Zuriel

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    Australia
    I am on Rivotril (Klonopin) and Lamictal which is another anti epileptic, but brain still fires (overstimulation, mental bombardment) all day and night. Anyone with similar experience? Dcotor's clinic is closed until the following week. Is this a symptom of neuropathy which is why I have severely slow stomach emptying? Have just started Freddd's protocol.
     
  2. Valentijn

    Valentijn Activity Level: 3

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    Amersfoort, Netherlands
    Rivotril acts by enhancing the neurotransmitter GABA, which acts by opposing the neurotransmitter glutamate. Lamictal inhibits the release of glutamate.

    One possibility in that glutamate and GABA levels aren't your problem.

    Another option is that reducing glutamate might be more effective the opposing and inhibiting it. In the case of ME/CFS, a cysteine deficiency is a likely cause of high glutamate levels, and both might be remedied by supplementing N-acetylcysteine. That's what I tried, and my over-stimulation and resulting sleeping problems are gone now.
     

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