Well, in late 2016, discovered that my B12 was 1600 (double the top of range) along with symptoms of B12 deficiency. That was from being on methyl B12. So I moved over to the Seeking Health Adensylcobalamin and Hydroxycobalamin. But alas, it's now "OVER 2000". And boy do I have fatigue now because of it. So as of two days ago, I moved to hydroxy only. I can't go without B12, or I start to have deficiency symptoms I'm sure this is all due to my now-active methylation mutations in MTRR, COMT and MTHFR 1298. My iron is now too high, too, at 166 for a female. So now I wonder--how in the world to get the B12 down. In addition to now moving over to hydroxy B12 as of two days ago, I've been on the follow supps for a few months---perhaps it takes even longer? Methylfolate 400 mg Betaine (restarted) B-vitamins by Seeking Health (without folate and methyl b12) Curcumin Phosphotidylcholine Nattokinaise D3 Probiotics And I'm now off of meat as of today. I have also been on 5 mg Lithium for two weeks. Would it help to move to 10 mg?