A good friend appears to have now had a healing startup which she never had before in all the years of taking MeCbl, occasional AdoCbl and 800mcg of L-methylfolate, and all the basics and others in her customized selection. Interestingly, I also have had a CNS healing startup for the first time since the disasterous glutathione (precursors) tiral I did with 9 others several years ago. If we were to assume a common factor for both of us, it corresponds to a larger daily dose of Enzymatic Therapy MeCbl (30-40mg for me, 2-3mg for her) AND almost daily AdoCbl, 3.3mg for both of us. After about 2 weeks she started needing more folate and then she needed more potassium. Well, my potassium which had been headed down, started back up. I got a larger effective dose of L-methylfolate via timing away from potassium and Vit C shortly after the insufficiency symptoms began. I've dropped 6 pounds in the last few days and my feet are ging through the pains progression towards returning feeling with it all ready back a little. Also the emotional intensity and turmoil that occurs with neurological healing. I am still recovering from last years crash from Jarrow gone bad MeCbl as well as the glutathione crash. I also retitrated SAM-e and eneded up at 800mcg this time instead of the 200 I used for years. I hadn't tested this since the glutathione. What we both have is almost daily AdoCbl from weekly and we both had some noticablestartup from the Anabol Dibencoplex. I have been trying to get a CNS healing startup since the glutathione (precursor) trial. She has never had a healing startup. The only thing that did ever give her a little startup was a one time CNS AdoCbl dose which has never repeated and didn't appear to turn healing on.