VDR Taq & Fok homozygous how much vitamin D

[kel88]

Hi Everyone,

Im homo for the VDR Taq and FOK.
Im COMT --
Does anybody knows how much vitamin D i should take? Some page said you dont have to take vitamin D because it can be toxic and other pages said that gou have to take much! Can anybody advise me?
My symptoms looks like Parkinson. I also got the gene mutations for parkinson..
And i should be low in dopamin when you are comt - and vdr taq + right?

Can anyone advise me?
They all said that i should be good on methyl donors but i doesnt ... Maybe because my CBS mutation ( homo) ?

 

[PointsNorth]

For MS I'm taking 70Kiu/day as per Dr. Coimbra's protocol. 1Kiu per kg. But you must follow his recommendations at this level.

PN

 

[kel88]

Hi PN!

Thanks for youre messags!
What is kiu sorry im from the netherlands so whe use other terms i think...
Would 5000iu be to much for me? In holland we dont have that much sunlight ( its a shame)..
And youve got MS no CFS? What are youre mutations ( SNPS) as i may ask?

 

[PointsNorth]

Hi kel,

1K is 1000 (at least in my shorthand ). I've been told that I have a genetic profile similar to someone with CFS. Many of the same mutations like MTHFR VDR.

In Western Canada where I'm from we sit under a cloud 10 months per year. From much reading I have done it is safe for an adult to take 10,000iu per day. https://www.google.ca/#q=vitamin+d+council. This is what you get (skin) from 20 min of mid-day summer sunshine.

PN

 

[taniaaust1]

Ive got no idea.. thou I have many of the same mutations as you. I also have parkinsons genes and also at one point was getting parkisons disease symptoms when I crashed bad. (I had a head matron of a hospital mistake me for a parkison's disease patient due to my symptoms she could see at the time, I had bad tremors).

For myself, trying to work out my D and how much to take was a trial and error thing for me (I still havent sorted it out). A blood test came back showing I was even more deficient then I was previously when I started supplementing with 2000IUs per day for 6months.. my specialist then had me put mine up to 5000IU per day (I never was retested again so have no idea if that got my levels then into a good range or not).

I personally suggest to go by how it makes you feel and by your blood tests for the vitamin. Have you had blood tests done to see how deficient you are?

 

[kel88]

Thanks both for youre reactions!

PN, you take 70.000iu? Woooow isnt that way to much? Do you also got bloodtest? And do you feel good with it? I always thought that the wetter was good in canada hihi...

@taniaaust1
Good to hear from another patient! I saw youre mutations.. The differece is only i got the other MTHFR mutation 1298C homo and you are 677C.
Youre luck is only that you have COMT mutations that makes dopamin more available and doesnt break it down quikly.
I got no COMT so i dont make much dopamin and break it down quikly ..

I will try parkinsons supplements!
Did you ever take NADH and Lithium?
What other supplements do you take? And what CBS mutation do you got? Do you also got sulfur problems?

I do bit also have BHMT mutations and AHCY
The mutations that dont stand in my signature are not good but "no call" what most of the time means a mutation also! I dont have much green in my panel ( ohh god...) haha

May i aks what youre symptoms are at the moment?
And can you look af my other post of parkinsons.. What are youre mutations when you look at the SNP"s from 23andme? I am so interesting if i really have parkinsons or that other ME patients also have the same mutations and it become a part of the ME-mutations!

I hope to hear from you
Thanks!