I think you misunderstood my post. What I meant was that I wasn't trying to convince you that you have CFS from that article. Some people who use these forums say they "have a B12 deficiency, but not CFS". I assumed you did not want to be labeled as having CFS for whatever reason. I'm not sure why you took that as an insult because that wasn't my intention at all. And since my response to your post had nothing to do with methylation or SNPs I didn't see the need for including those lines "for context". I don't necessarily disagree with you either about being many triggers leading to the same illness, but if you think that then I don't know why you don't say you have CFS/ME. Lyme disease seems to be the cause of my illness. I don't know if that means I have CFS/ME or not. I'm not really concerned with labels. Some people have suggested that Lyme disease is an autoimmune condition. I don't know if that's true or not, but there doesn't seem to any consensus on that. I'm also not sure how much that has an impact on treatment. Someone told me about the HERV information when that article came out because they thought it was significant, but I haven't read through the article myself. I'm more interested in things that I can immediately apply to my own health. That's also why I haven't spent much time learning about the theory behind methylation as far as what is actually going on. I don't have the brainpower for that kind of stuff right now, but maybe later I would like to have a greater understanding of these subjects.