Just spoke to a cfs friend who told me his cfs daughter uses the hormone vasopressin nasal spray. She would go to the toilet all the time and the nasal spray has helped alot. Seems like it could be very helpful for pots/oi. electrolytes have there place but if we keep peeing it out we are just chasing our tails, literally. It seems more direct then other sodium retention type hormone treatments. Also another thing i havent heard anyone mention is glycerol. i remember years ago reading how athletes were using this to help maintain hydration as it help them to keep fuid balance in their favour and reduce chances of dehydration. cheers!!