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Vasopressin - Bingo

Discussion in 'Problems Standing: Orthostatic Intolerance; POTS' started by xks201, Apr 9, 2012.

  1. ramakentesh

    ramakentesh Senior Member

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    Also DDVAP can greatly increase the propensity of a person to form blood clots, making it quite dangerous.
     
  2. sensing progress

    sensing progress Senior Member

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    Tucson, AZ
    I have been trying to find a doctor who will prescribe Desmopressin for a while now. A few years ago I benefited greatly from taking salt tablets, which I believe helped me to retain water and thus boost my blood volume back to normal. However, the effect wore off after about a month. I have always wondered if Desmopressin would sustain that same effect, but no luck in getting it so far.
     
  3. CBS

    CBS Senior Member

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    Western US
    Unless of course your body is not producing a sufficient/normal level of vasopressin in which case without DDAVP you're at a greater risk of inadequate clotting and bleeding out. Also keep in mind that the viscosity of the blood in hypovolemic patients (who may be losing too much fluid and be in need of DDAVP) is increased leading to an elevated risk of cardiovascular problems. It just might be a bit dangerous to throw around phrases like "making it quite dangerous" when the potential for danger is relative and based largely on circumstance.

    Can DDAVP be dangerous? Yes, in the wrong patient and/or at the wrong dose.

    Can it save your life? Absolutely - if you need it.

    I do not recommend even considering it without the guidance of an endocrinologist WITH experience in treating DI. I can almost guarantee that even your above average PCP does not know enough about this drug to prescribe it safely (and clotting isn't the first thing on the list of factors to be concerned about).
     
    zzz, ahimsa and sensing progress like this.
  4. fairlight

    fairlight

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    Droxidopa ia currently in clinical trials for this and other disorders. http://clinicaltrials.gov/ct2/results?term=droxidopa
    Hopefully it'll be available in the near future. I take midodrine sometime, which helps. I've had POTS as far back as 6th grade. I would always take baths because I didn't want to stand in the shower. I also hated going to museums because my parents would stand in front of each display and read about the display, for what seemed like hours. My body would start to hurt and I felt like passing out. I never knew why I felt so poorly when I stood in one place, or bending down and standing up a few times in a row could send me to bed for several hours. It was horrible and I never knew why I felt so bad.

    I'm hoping that droxidopa will be approved in the near future. It's approved in Japan.
     
  5. ramakentesh

    ramakentesh Senior Member

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    Droxidopa has not been trialled clinically for POTS but may for the neuropathic variety
     

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