It just occured to me that pretty much all the curative or partially curative treatments being trialled in ME are of this kind: Chia uses Oxymatrine to get rid of Enteroviruses; KDM uses antibiotics to get rid of Lyme; Fluge and Mella use Rituximab to get rid of certain autoantibodies (I know this is just one of their potential theories as to how it works, but as far as I´m aware they are all sledgehammers). It seems to me that, whoever is right about the ultimate cause, the real challenge is developing a nutcracker for that problem (nut). The fact that they are all using sledgehammers to get results also means that it is hard to determine exactly what kind of nutcracker is required (okay, the analogy sort of falls apart here, but hopefully you get the idea). So, what kind of nutcracker do you think we need? I would say we need antibiotics that target persisters.