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Update from Haukeland about the RituxME study

Discussion in 'General ME/CFS News' started by mango, May 11, 2016.

  1. mango

    mango Senior Member

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    http://me-forskning.no/oppdatering-fra-haukeland-om-rituxme-studien/

    Translated by Google:
     
  2. Tuha

    Tuha Senior Member

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    It would be interesting to know more exactly about their research on autoantibodies, immune signatures, cell metabolism and genetics. Do we know more about?
     
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  3. Riley

    Riley Senior Member

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    Louisiana
    That bio bank has the potential to be an absolute game changer.
     
  4. BurnA

    BurnA Senior Member

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    Yes especially when they can identify the responders, relaspers and the non repsonders once the blinding is removed.
     
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  5. voner

    voner Senior Member

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    here's about a-year-old piece written for the Kalvi trust's website that I found to be packed with general information about the activities of The Haukeland team. Perhaps it has been posted here before, but it's worth rereading.

    some quotes:

    http://kavlifondet.no/2015/04/tackling-a-medical-mystery/
     
    Last edited: May 11, 2016
  6. mango

    mango Senior Member

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    Does anyone happen to have more info/details about the methods used to measure flow-mediated dilation and skin microcirculation in the RituxME endothelial dysfunction substudy (or possibly the main RituxME study)?

    I've already checked the study protocol etc, but haven't been able to find what I'm looking for, i.e. the formal/medical terms for the two (or more?) ways of measuring blood circulation/endothelial function.

    Bob mentioned ultrasound and "a slightly different method" in a post a while ago, and @deleder2k mentioned nitroglycerin here.

    @Marky90? @Kalliope? Anyone else?
     
  7. Kalliope

    Kalliope Senior Member

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    Norway
    This is from a powerpoint from prof. Olav Mella during his lecture in Stavanger, Norway in November last year. Is this what you were looking for, @mango ?
    • Endothelia dysfunction: the capacity to expand supplying vessels according to stimuli.
      - For big vessels: FMD (measured by ultra sound) (Bergen and Notodden).
      - For small vessels: POHR analysis (Bergen)


     
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  8. mango

    mango Senior Member

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    Ooh, super helpful! Thank you so much, I really appreciate it :)
     
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