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under what circumstances does folate metabolism reverse direction?

Discussion in 'Detox: Methylation; B12; Glutathione; Chelation' started by forbius, May 5, 2015.

  1. forbius

    forbius

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    As per this diagram

    [​IMG]
    These reactions are bidirectional. I assume the 'normal' direction is that which results in +1 glycine outside mitochondria and +1 serine inside (or am I wrong?). What conditions cause this to change?
     

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