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UK, The Times, 23 Apr: 'Biological breakthrough offers fresh hope to ME sufferers

Discussion in 'General ME/CFS News' started by filfla4, Apr 23, 2013.

  1. filfla4

    filfla4 Senior Member

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  2. snowathlete

    snowathlete

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    My mum just sent me this too. Interesting.
    Allyson likes this.
  3. MeSci

    MeSci ME/CFS since 1995; activity level 6

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    Allyson likes this.
  4. SilverbladeTE

    SilverbladeTE Senior Member

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    Somewhere near Glasgow, Scotland
    *hammers another nail in the metaphorical and proffessional coffin of Wessely, White et al and the UK government!*
    August59, Tristen, golden and 3 others like this.
  5. lansbergen

    lansbergen Senior Member

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    I can not find anything but from what is in the newspaper it looks good


    Scientists provide fresh hope for ME sufferers
    ----------------------------------------------

    Scientists have found compelling new evidence for an underlying
    biological cause for the constant fatigue suffered by ME patients. The
    study revealed abnormalities in the muscle cells people suffering from
    ME which are likely to contribute to feelings of tiredness and the
    inability to cope with sustained physical activity that many
    experience. An analysis of muscle biopsies suggested that the cells
    had undergone substantial changes making them less able to cope with
    exertion. The finding shows that whatever the initial trigger for ME,
    the condition leads to a cascade of physical changes right down to the
    cellular level
  6. Sasha

    Sasha Fine, thank you

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    Great! Thanks for posting.

    The start of the article (which allows comments) is available online but the full thing (presumably including the ability to comment) is behind a paywall:

    http://www.thetimes.co.uk/tto/science/article3746102.ece

    Any subcribers who can comment and mention the UK biomedical charities, or Maria's Rituximab fundraising drive? I think these kind of articles attract PWME who aren't even aware that these charities exist. I think they're a good recruiting ground.
  7. Allyson

    Allyson *****

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  8. Sasha

    Sasha Fine, thank you

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    filfla4, I hope you don't mind but I'm asking the moderators for a more specific title for this because I think it's important and a lot of UK people will be interested. I'm suggesting, 'UK, The Times, 23 Apr: 'Biological breakthrough offers fresh hope to ME sufferers'.

    Thanks again for posting - this cheered me up no end! :)
    Allyson likes this.
  9. Allyson

    Allyson *****

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    y\

    yes and on fb the news travels really quickly too Sasha
    CHeers,
    Ally
    Sasha likes this.
  10. filfla4

    filfla4 Senior Member

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    Sure Sasha, good idea.
    Allyson and Sasha like this.
  11. Enid

    Enid Senior Member

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    Aaaaah - are we getting somewhere now - it's been a awful long 12 years ! Thanks for posting filfla. Invest in ME London conference coming up in early May (recent researches) and Dr Gerada (RCGP) attending too. She is of course SW's wife, with hopefully some influence on the all in your minders I had to meet a few years ago.
    Allyson, golden and justy like this.
  12. Esther12

    Esther12 Senior Member

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    Newton has previously been using deconditioned control groups, so this could be interesting.

    I should probably not comment until we've seen the final paper... but I'm always cynical about the claims of CFS research! I think that there have been past papers on similar findings too, although I can't remember the details.
    Allyson likes this.
  13. Kina

    Kina Moderation Team Lead

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    I have changed the title.

    Great article. :)
    beaker and Allyson like this.
  14. Desdinova

    Desdinova Senior Member

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    Good news but I'll have too wait a while before I do my happy dance followed by my I told you so dance. Somewhere as we type Weasel - Whitewash and Co are busy planing a counter (debunking) offensive.
  15. snowathlete

    snowathlete

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    This *could* be a positive from the new collaborative. i.e. Newton having got involved with it, gets access to papers etc?
    Allyson likes this.
  16. alex3619

    alex3619 Senior Member

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    This is semi-old news, I think, but what is new is that the media is picking up on it. That is a good sign. It might also be that I am misremembering as similar research was done on OI if I recall correctly, and the CFS study is really new. Either way, I like this trend of isolating tissue and then subjecting it to tests under stress in controlled conditions. Its paid off for OI, and FM, and now maybe CFS. Hard to study stuff is easier to study if its isolated, though you then lose the complexity of interaction that may make things happen differently in the body.

    Now if they did cytokine testing and energy production testing under these conditions, would we get diagnostic biomarkers?
  17. alex3619

    alex3619 Senior Member

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    We saw the debunking/denial with H. pylori. 23 years after Barry Marshall showed H. pylori caused gastric ulcers, and more than a century after it was first suspected, White et. al. were discussing it as though psychosocial factors were really important, more so than the biological (2005, White's book whatever it was called - Biopsychosocial Medicine? I would have to look it up and I couldn't be bothered as I am about to go to bed). Yet now we see more and more of them embracing bioscience. Is it because they discovered that bPS actually has a B in it? Or is it that they are looking for biomarkers, as I have suggested a few times now, so that they can try to legitimize psychogenic views or not look just plain silly? Or has there really been a paradigm shift, or we are seeing the beginning of one? Take your pick, but I think if we want a paradigm shift we (and others including medical scientists and psychiatrists) are going to have to create one.
    Desdinova and Allyson like this.
  18. Gijs

    Gijs Senior Member

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    This is not semi-old news. This finding is verry important. For the first time Prof. Newton shows that high lactid is not due to deconditioning etc... but there is a celular problem. This is really a breakthrough.
  19. Gijs

    Gijs Senior Member

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    You can throw away the deconditioning theories if Dr. Newton’s new study comes out; she finds abnormalities in cellular metabolic functioning they cannot be explained away by deconditioning, behavioral problems, etc
    justinreilly and Allyson like this.
  20. Bob

    Bob

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    The full article is on the ME Association's website:
    http://www.meassociation.org.uk/?p=15215

    Essential info from the article:

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