Hey all, I did freddds methylation protocol back in August 2012, which is about a 2 months after coming down with cfs. I did it for about 2.5 months and experienced a lot of benefits, but by the end of the 2.5 months started to feel very weak/no energy to the point that I was struggling to use my breathing muscles. When I look back now I think it could have been an increased need for potassium even though I was drinking a lot of coconut water at the time too. Or it cou;ld have been due to mercury chelation from the Alpha lipoic acid I was also taking at the time. I didn't know anything about amalgam illness/ chelation last year. I stopped all supplements cold turkey and began recovering and by november/december It was like I never had cfs. I think my partial methylation black had been lifted those two months. Actually I didn't think it was cfs at the time but a severe b12 deficiency. Come Jan 2013-present I have been up and down struggling seeing a couple specialist here and there, finding many abnormal findings with immune systemm, heavy metal, infection, etc. Diagnosed with CFS/FIBRO. Now that I understand a lot more than last year I think it's time for me to try the methylation protcol again before I tackle my heavy metals and infections. Right now my current condition is HOUSEBOUND/BEDBOUND(somedays) Main Symptoms include: Diarrhea with abdominbal pain Headaches Ears ringing fascilations dizziness vertigo blurry vision low energy shortness of breath wake up many times during sleep anxiety post exhertional malaise neuropathy(pins and needles/ loss of sensations) Fat and acidic food intolerance I am gonna keep my progress on this thread and hopefully can cross each starting symptom off as the months go by. I am going to go much slower with dosing and not go up to megadoses. I am aware of potassium deficit this time around and will not include the ALA. Here is my nutreval and 23andme snps. If anyone has any tips or suggestions I will gladly listen.