Oxidative stress is implicated in most human diseases. Antioxidants may decrease the oxidative damage and its alleged harmful effects. Many people are taking antioxidant supplements, believing to improve their health and prevent diseases. Whether antioxidant supplements are beneficial or harmful is uncertain. Many primary or secondary prevention trials of antioxidant supplements have been conducted to prevent several diseases. Read more... 'Data Extraction: We included 68 randomized trials with 232 606 participants (385 publications).' An interesting read, though I am wondering if the included 68 trials might have been pre-selected based on their findings. Are there other studies out there which would contradict this paper?