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Trial By Error: MEGA’s Latest Failure

Discussion in 'General ME/CFS News' started by AndyPR, Sep 18, 2017.

  1. AndyPR

    AndyPR Senior Member

    http://www.virology.ws/2017/09/18/trial-by-error-megas-latest-failure/
     
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  2. lilpink

    lilpink Senior Member

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    This is one blog I have especially enjoyed reading. Oh MEGA!
     
  3. SilverbladeTE

    SilverbladeTE Senior Member

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    Somewhere near Glasgow, Scotland
    The only thing I'd praise Esther Crawley for would be for her magnificent malignity, her stupendous stupidity, and fabulous f***wittery!

    or, if she stepped into a Gravitational Collapsar....

    :p
     
  4. Research 1st

    Research 1st Severe ME, POTS & MCAS.

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    MEGA was timely chosen. It's a MEGA Fail for PWME.

    Although EPIC might have been a better acronym to use.
     
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  5. BurnA

    BurnA Senior Member

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    It may not be.

    It is a MEGA fail for the CMRC and it could be a turning point for PWME - it indicates that funding may not be so readily supplied to poor studies.
     
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  6. Woolie

    Woolie Senior Member

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    I don't share Tuller's optimism. I think this proposal got way too close to being funded, and that worries me.

    Even if you put aside Crawley's objectionable theoretical framework, its clear to me she's not really not equipped to do research at the highest level. There appear to be a number of projects she was funded to do many years ago, which she has not yet reported on. And recently, Ive seen publications form her lab appearing in very strange journals, which suggests she may be failing to get her work past reviewers in more reputable outlets.

    When you compare her work to that of the PACE investigators, there is a huge difference in quality. Say what you want about the PACE folks, they look like the creme-de-la-creme when compared to Prof. Crawley.
     
  7. Esther12

    Esther12 Senior Member

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    LOL - I really enjoyed that blog, and the sign off in the e-mail to the CMRC. (Certainly compared to all the other things I've been reading today).

    That I found Holgate's talk so annoying in other ways stopped me from appreciating the good news that MEGA failed to get MRC funding. I don't know enough about how funding decisions are made to know if Woolie's concern about it getting so far outwieghs the good news that they're not getting any cash, but I do think that they had a lot of political advantages on there side here, and that they still were not able to get funding is surely a good sign.

    Remember when they launched that petition last year with a "Yay - we can do it if we all work together" sales pitch to get patient support for more money going to Crawely? If we knew then that they were going to get turned down by both Wellcome and the MRC I'd have been pretty pleased about that. They had a plan, and it's not going well.

    I'd have felt gutted if they had got funding, so I want to get some pleasure from the fact that they haven't!
     
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  8. lilpink

    lilpink Senior Member

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    Don't forget the OMEGA bods saw through their cunning ways even whilst others were singing (and still do) the praises of the CMRC tent. (Who seriously ever thought a tent with an EC shaped pole was going be good for us? )

    Continue to support OMEGA because our lives actually do depend on having an alternative voice. Continue to share and continue to sign: https://www.change.org/p/opposing-m...autopublish&utm_term=des-lg-no_src-reason_msg
     
  9. user9876

    user9876 Senior Member

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    I agree that her research output is poor. I would have thought that they got to the interview state via political pressure. I also think a 'well-styled' but largely meaningless proposal can get a long way as reviews often don't dig into detail. Only when choices are made are details really thought through.
     
  10. Woolie

    Woolie Senior Member

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    You could be right. In my country, our grants application system also has two stages. Stage 1 needs a short spiel with a compelling idea. It needs to grab the panel's attention, to sound novel.

    Stage 2 involves writing a full proposal which then goes out to peer reviewers who comment in detail and rate the application.

    So yea, you can get through Stage 1 with a sexy idea, but to get through Stage 2, you gotta have some teeth behind that idea.

    Maybe its the same at the MRC?
     
  11. A.B.

    A.B. Senior Member

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    Nice compliment-insult.
     
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  12. user9876

    user9876 Senior Member

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    I've no idea with the MRC or any UK research panels. I got a grant from a different organisation that funds some industrial research that works that way.

    I was thinking even a well-written but not very interesting proposal can get through a first peer review.
     
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  13. TiredSam

    TiredSam The wise nematode hibernates

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    Do I detect a slight change in tone from Tuller? A little more Coyne-esque?
     
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  14. Emma

    Emma

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    Oh, that's a worry. I think we need critiques to be as factual and as cordially phrased as possible, to have impact outside of the ME circle.
     
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  15. Barry53

    Barry53 Senior Member

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    Maybe the funding bodies had got wind of the up-coming NICE report? Suddenly things didn't look to be such a good investment maybe. In which it may not have got as close as might seem.
     
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